About This Peptide
TB-500 is a synthetic peptide containing the active region (LKKTETQ) of Thymosin Beta-4 (TB4), a naturally occurring 43-amino acid protein found in high concentrations in blood platelets, white blood cells, and wound fluid. Its primary function revolves around actin sequestration, cell migration, and tissue remodeling. By enabling repair cells to move quickly to sites of injury, TB-500 accelerates healing across tendons, ligaments, muscle fibers, corneal tissue, and cardiac muscle.
Primary Actions in the Body
- Actin Sequestration & Cell Migration: TB-500 binds to G-actin (globular actin) to regulate filament assembly. This dynamic actin remodeling allows fibroblasts, endothelial cells, and stem cells to rapidly migrate through tissue matrixes to reach injured areas and initiate structural repair.
- Angiogenesis (New Micro-Vessel Formation): It stimulates the growth of new capillaries from existing blood vessels. Re-establishing micro-circulation to low-vascularity connective tissues (like tendons, ligaments, and cartilage) ensures an ongoing supply of oxygen and nutrients required for recovery.
- Downregulation of Chronic Inflammation & Fibrosis: TB-500 decreases pro-inflammatory cytokines and suppresses excessive collagen deposition, helping prevent dense, inflexible scar tissue from forming in healing muscles and ligaments.
- Cardiovascular & Tissue Protection: In pre-clinical cardiovascular studies, Thymosin beta-4 derivatives have demonstrated cardioprotective effects following ischemic injury by preserving myocardial cell survival and reducing scar formation.
- Hair Follicle & Dermal Support: By promoting cell migration and angiogenesis around hair follicles, it can support stem cell migration to dermal papillae, stimulating hair growth and skin regeneration.
Is This Right For You?
Patients often come to us interested in this treatment for healing an injury, easing joint pain, or recovering from a strain. If that sounds like what you’re looking for, our provider can walk you through whether it’s a good fit for your goals during your consultation.
Ordering & Shipping
New Patient Package. This price includes your initial in-person consultation, physical consultation with our licensed provider at New Jersey Trim Clinic, and the product itself. After checkout, you will receive an order confirmation email thanking you for your order. Our team will then contact you by text, phone, or email to schedule your provider appointment in-person or telehealth. Medication will be ordered and shipped 2-day air ($15 charge) to you after our provider confirms this treatment is appropriate for you. If our provider determines this product is not appropriate for you, a 100% refund will be issued.
For use only under the guidance of a licensed medical provider. Individual results vary. This description is for informational purposes only and does not constitute medical advice.






