Existing prescription required for this specific peptide. This refill option is only for patients with an active New Jersey Trim Clinic prescription for this exact peptide already on file. If you do not currently have one, you will need to complete a paid Doctor Consultation ($60) first so our provider can determine whether it is right for you before it can be prescribed.
About This Peptide
Dihexa (PNB-0408) is an experimental, orally active peptide derivative that functions as a potent neurogenic and synaptogenic compound.
It was originally developed by researchers at Washington State University as a candidate drug to repair brain tissue and reverse cognitive decline associated with neurodegenerative conditions like Alzheimer’s disease.
Primary Mechanism of Action Dihexa acts as a high-affinity ligand for HGF (Hepatocyte Growth Factor) and its receptor, c-Met:
- Activates the HGF/c-Met Pathway: By binding to HGF, Dihexa dramatically potentiates its activity at the c-Met receptor, triggering intracellular signaling cascades involved in cell survival and growth.
- Promotes Spinogenesis & Synaptogenesis: It stimulates the rapid formation of new dendritic spines and synaptic connections between neurons in the brain, specifically in regions like the hippocampus, which controls memory and learning.
- Enhances Neuroplasticity: Research models indicate it can repair damaged neural networks, helping restore cognitive function, memory formation, and processing speed.
Is This Right For You?
Patients often come to us interested in this treatment for sleeping better, easing anxiety, or sharpening focus and memory. If that sounds like what you’re looking for, our provider can walk you through whether it’s a good fit for your goals during your consultation.
Ordering & Shipping
Refill for existing patients. This option requires an active New Jersey Trim Clinic prescription for this specific peptide already on file. After checkout, you will receive an order confirmation email thanking you for your order. Medication will be shipped 2-day air ($15.00) only after our provider confirms this refill treatment is appropriate for you. If you do not currently have a prescription for this peptide with us, please complete a paid Doctor Consultation ($60) first so our provider can evaluate whether it is right for you before it can be prescribed. If our provider determines this product is not appropriate for you, a 100% refund will be issued.
For use only under the guidance of a licensed medical provider. Individual results vary. This description is for informational purposes only and does not constitute medical advice.







