About This Peptide
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. It is a synthetic analog of the naturally occurring human immunomodulatory peptide tuftsin, with a stabilized C-terminal sequence to extend its half-life and biological activity.
Functioning primarily as an anxiolytic (anti-anxiety) and nootropic (cognitive enhancer), Selank is designed to relieve stress and anxiety without causing sedation, addiction, physical dependence, or cognitive impairment.
Primary Actions in the Body
- GABAergic Modulation & Anxiety Reduction: Selank modulates GABA-A receptors, enhancing the inhibitory action of gamma-aminobutyric acid (GABA) in the central nervous system. This produces a calming, anti-anxiety effect similar to traditional tranquilizers (like benzodiazepines), but without causing muscle relaxation, drowsiness, or memory impairment.
- Enkephalin Stabilization & Mood Enhancement: Selank inhibits the enzymes that break down endogenous enkephalins (the body’s natural opioid peptides). By preventing their degradation, it elevates circulating enkephalin levels, which helps stabilize mood, improve stress tolerance, and promote an overall sense of well-being.
- Neurotransmitter Regulation (Dopamine & Serotonin): It influences the metabolism of serotonin and dopamine in the hippocampus and cortex. This neurochemical balance supports motivation, mental focus, and emotional regulation during high-stress periods.
- BDNF Upregulation & Neuroprotection: Selank stimulates the expression of Brain-Derived Neurotrophic Factor (BDNF) in the hippocampus. BDNF supports neuroplasticity, memory formation, synaptic health, and learning capacity.
- Immunomodulatory Activity: Inherited from its parent peptide tuftsin, Selank alters the expression of certain cytokines (such as IL-6) and supports natural immune cell activity, helping buffer the immune system against stress-induced suppression.
Is This Right For You?
Patients often come to us interested in this treatment for sleeping better, easing anxiety, or sharpening focus and memory. If that sounds like what you’re looking for, our provider can walk you through whether it’s a good fit for your goals during your consultation.
Ordering & Shipping
Refill for existing patients. After checkout, you will receive an order confirmation email thanking you for your order. Medication will be shipped 2-day air ($15.00) only after our provider confirms this refill treatment is appropriate for you. If our provider determines this product is not appropriate for you, a 100% refund will be issued.
For use only under the guidance of a licensed medical provider. Individual results vary. This description is for informational purposes only and does not constitute medical advice.






