Existing prescription required for this specific peptide. This refill option is only for patients with an active New Jersey Trim Clinic prescription for this exact peptide already on file. If you do not currently have one, you will need to complete a paid Doctor Consultation ($60) first so our provider can determine whether it is right for you before it can be prescribed.
About This Peptide
PT-141 (also known as Bremelanotide) is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (alpha-MSH).
Unlike traditional erectile dysfunction or arousal medications (such as PDE5 inhibitors like sildenafil or tadalafil) that work peripherally on blood vessels, PT-141 acts directly on the central nervous system to stimulate sexual desire and arousal in both men and women.
Primary Actions in the Body
- Central Nervous System Arousal (MC3R / MC4R Agonism): PT-141 crosses the blood-brain barrier and binds as an agonist to melanocortin 3 (MC3R) and melanocortin 4 (MC4R) receptors in the hypothalamus. This triggers neural pathways that govern sexual motivation, desire, and autonomic arousal.
- Treatment of Hypoactive Sexual Desire Disorder (HSDD): In women, central MC4R activation helps modulate excitatory and inhibitory neural pathways in the brain, increasing feelings of sexual desire and reducing related distress.
- Erectile Function Improvement in Men: In men, hypothalamic melanocortin stimulation activates descending autonomic signals to the pelvic vascular bed. Because it works via neural pathways rather than direct nitric oxide/vascular pathways, it can produce erections even in cases where vascular medications are ineffective or contraindicated.
- Independent of Vascular Dilation: It does not rely directly on the cardiovascular system or localized smooth muscle relaxation to initiate arousal, making its mechanism fundamentally distinct from sildenafil (Viagra) or tadalafil (Cialis).
Is This Right For You?
Patients often come to us interested in this treatment for improving intimacy or sexual wellness. If that sounds like what you’re looking for, our provider can walk you through whether it’s a good fit for your goals during your consultation.
Ordering & Shipping
Refill for existing patients. This option requires an active New Jersey Trim Clinic prescription for this specific peptide already on file. After checkout, you will receive an order confirmation email thanking you for your order. Medication will be shipped 2-day air ($15.00) only after our provider confirms this refill treatment is appropriate for you. If you do not currently have a prescription for this peptide with us, please complete a paid Doctor Consultation ($60) first so our provider can evaluate whether it is right for you before it can be prescribed. If our provider determines this product is not appropriate for you, a 100% refund will be issued.
For use only under the guidance of a licensed medical provider. Individual results vary. This description is for informational purposes only and does not constitute medical advice.





